HEV IgM- first HEV IgM ELISA diagnostic kit which utilizes “Antibody Capture Method”

Hepatitis E, which was previously called enterically transmitted non-A non-B hepatitis, is caused by infection with hepatitis E virus (HEV), an RNA virus that is still unclassified. HEV is transmitted through the fecal-oral route, predominately through contaminated water or food supplies with sporadic outbreaks.

The early detection of HEV antibodies is critical for the efficient treatment and prevention of the spread of the disease and in comparison with other diseases, detection of IgM antibodies can be a reliable marker for acute infection. Although assays for detection of HEV IgM are available, this approach is still not applicable for routine diagnosis due to the insufficient performances of sensitivity and specificity, high rate of false negative results ,the method employed (indirect ELISA), and because of the quality of the proteins applied with the commercially available kits. Moreover, most of the available HEV – IgM kits can detect IgM positive seroconversion, late after IgG is already detected positive.

Wantai HEV IgM ELISA assay is sensitive and specific and is very useful for the early diagnosis of acute hepatitis E. It overcomes the low sensitivity of the traditional assays, and can precisely distinguish current from past HEV infection.

It is the first HEV IgM ELISA diagnostic kit which utilizes “Antibody Capture Method” thus with better sensitivity and specificity.

Other Features of HEV IgM:

• Qualitative Assay

• Sample.......................................... 10µl,

• Test principle............................... The First commercially available Antibody "capture" ELISA assay

• Short incubation time................. 30min. + 30min. + 15min.

• Specificity > 99%, Sensitivity is 97.1%