Hepatitis E virus - The leading cause of acute viral hepatitis in the world
WANTAI HEV ELISA KITS :
Wantai HEV ELISA kits use a recombinant capsid Ag (E2) expressed from highly conserved region of ORF2 of the HEV
Wantai HEV IgM ELISA: IgM is the most reliable marker for acute infection. The “Mu capture” method of our test overcomes the low sensitivity of the traditional “indirect” assays. The kit precisely distinguishes current from past infection with the virus.
Wantai HEV IgG ELISA : Suitable for epidemiological studies and as an aid to the clinical diagnosis of hepatitis E.
Wantai HEV total antibodies ELISA : Worldwide animal infection eastablishes HEV in the place of zoonosis. Therefore, the correct diagnosis is important for understanding of HEV and its zoonosis-related issues.
Wantai HEV Ag ELISA : Intended for detection of viral antigens.
Wantai Hepatitis E Virus Diagnostic Kits
Wantai HEV ELISA kits use a recombinant capsid Ag (E2) expressed from highly conserved region of ORF2 of the HEV.This Ag expresses some important conformation Antigenic epitopes of the native virus and shows extremely high reactivity to HEV specific antibodies . The ORF -2 region in the HEV can dimerize with an increasing reactivity in HEV convalescence sera. Wantai ELISA kits are based on the use of these dimers which have shown an improved sensitivity as compared to other ELISA s (lower limit of detection for HEV IgG is 0.25 WHO units/ml and showed higher positively in sera from proven cases i.e. 98 % and also remained positive for a longer post – infection period).
HEV IgM based on Mu Capture principle.
Among study group of 16865 individuals, (including 7113 blood donors), the specificity of Wantai HEV-IgM is 98.8%. In testing of acute hepatitis A, B and C sera, the overall specificity is 95.3%
HEV Ag ELISA